Intrahepatic Cholestasis in Pregnancy: An Overview and Update

Intrahepatic Cholestasis of Pregnancy (ICP) is a liver disorder that specifically occurs during pregnancy, typically in the third trimester. It is characterized by impaired bile flow within the liver, leading to the accumulation of bile acids in the bloodstream. While the exact cause is not fully...

• Obstetric Cholestasis (OC), also known as Intrahepatic Cholestasis of Pregnancy (ICP), is a liver disorder specific to pregnancy, affecting about 1% of pregnancies. It involves impaired bile flow, leading to elevated bile acids in the bloodstream. Genetics, hormonal influences (estrogen and progesterone), and environmental factors (selenium deficiency) contribute to the condition.