
CASE DISCUSSION
Nephrotic Syndrome in Children: Clues to Recognise
Presented from by Dr. Baldev Prajapati
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Case Description
Nephrotic syndrome in children is a common pediatric kidney disorder characterized by heavy proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Early recognition is crucial, as children often present with puffiness around the eyes, swelling of the face and limbs, frothy urine, and unexplained...
Case Summary
- Nephrotic syndrome in children is characterized by nephrotic-range proteinuria (over 40 mg/m2/hr, 100 mg/m2/day, or a protein/creatinine ratio > 2), hypoalbuminemia (albumin < 3 g/dL), and generalized edema. Hyperlipidemia, previously part of the definition, is no longer included. In children, the most common cause is idiopathic, with minimal change disease accounting for around 80% of cases. Secondary causes, seen in about 10% of cases, include systemic diseases like SLE, infections (hepatitis, malaria), and drug-induced nephrotic syndrome.
Speaker Profile

Dr. Baldev Prajapati
Senior Consultant Pediatrician, Akanksha Children Hospital, AhmedabadDr. Baldev Prajapati , Senior Consultant Pediatrician, Akanksha Children Hospital, Ahmedabad
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