CASE DISCUSSION
Newer Biochemical Bone Health Markers
Presented India by Dr. Sangeeta KapoorViews
206
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Case Description
Bone remodeling is a continuous, tightly regulated process governed by the coordinated activity of osteoblasts and osteoclasts through the Wnt-beta-catenin and RANK-RANKL-OPG signaling pathways. Although traditional metrics such as total serum alkaline phosphatase and urinary hydroxyproline remain...
Case Summary
- Bone remodeling is a continuous, tightly regulated process involving the coordinated activity of osteoblasts and osteoclasts, governed by the Wnt-beta-catenin and RANK-RANKL-OPG signaling pathways. While traditional markers like total serum alkaline phosphatase and urinary hydroxyproline are widely available, they often lack specificity due to their expression in multiple tissues. Clinical practice is shifting toward more robust, bone-specific markers that better reflect real-time bone turnover.
Speaker Profile
Dr. Sangeeta Kapoor
Professor & Head, VIMS Hospital, Uttar PradeshDr. Sangeeta Kapoor is a distinguished academician and clinician serving as Professor & Head at VIMS Hospital, Uttar Pradesh. With extensive experience in patient care, teaching, and clinical leadership, she has contributed significantly to advancing evidence-based medical practice and training future healthcare professionals. Dr. Kapoor is actively involved in academic initiatives and professional education, making her a respected voice in her field. Her expertise and commitment to quality healthcare continue to inspire clinicians and students alike.
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