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CASE DISCUSSION

Postbiotics, Prebiotics and Probiotics: From Hype to Clinical Evidence

India flagPresented India by Malvika Fulwani

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Case Description

Probiotics, prebiotics, and postbiotics are gaining attention for their potential role in gut health and disease management. This session will explore their mechanisms of action, effects on the gut microbiome, and emerging clinical applications across gastrointestinal and metabolic disorders. It...

Case Summary

  • Microbiome-targeted therapies, encompassing prebiotics, probiotics, postbiotics, and synbiotics, require a transition from mechanistic plausibility to rigorous, indication-specific clinical evidence. The gut microbiome functions as an interactive ecosystem rather than a detoxifying organ, influencing mucosal barrier integrity, immune signaling, short-chain fatty acid production, and metabolic pathways. However, vague terminology such as leaky gut lacks clinical utility, and microbial alterations in conditions like irritable bowel syndrome and metabolic dysfunction-associated steatotic liver disease do not inherently prove causality.

Speaker Profile

Malvika Fulwani

Malvika Fulwani

Chief Dietitian, Healthitude, Nagpur
Malvika Fulwani is a Clinical Dietitian and a Certified Diabetes Educator with over eight years of dedicated service specializing in women’s health, metabolic disorders, lifestyle disorders, and diabetes..Her expertise lies in providing specialized dietary guidance and education to individuals managing diabetes and other metabolic disorders like Hypothyroidism, PCOS, infertility, and hypertension. With a strong passion for advocacy and education in diabetes and women's health, Malvika raises awareness about the condition and its management strategies

Disclosures

Assimilate by Medvarsity requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant financial relationships for anyone with the ability to control the content of this educational activity have been reviewed and mitigated. Others involved in the planning of this activity have no relevant financial relationships.
Postbiotics, Prebiotics and Probiotics: From Hype to Clinical Evidence