Transposition of Great Arteries: An Overview

Transposition of the Great Arteries (TGA) is a congenital heart defect where the two main arteries that carry blood away from the heart, the aorta and the pulmonary artery, are switched in position. In a normal heart, the aorta arises from the left ventricle and carries oxygen-rich blood to the...

• Transposition of the Great Arteries (TGA) is a cyanotic congenital heart defect where the aorta arises from the right ventricle and the pulmonary artery from the left ventricle, leading to parallel rather than serial circulation. This condition is incompatible with life unless there is mixing of oxygenated and deoxygenated blood via an atrial septal defect (ASD), ventricular septal defect (VSD), or patent ductus arteriosus (PDA). The severity of cyanosis depends on the degree of mixing.